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CAS 28578-16-7: Properties, Synthesis, and Applications


CAS 28578-16-7, also known as (2-Bromo-1-phenyl-1-pentanone), is a chemical compound with diverse applications in organic synthesis and pharmaceutical manufacturing. Its unique chemical properties and reactivity make it a valuable building block for the production of various organic compounds and specialty chemicals.

Chemical Structure and Composition:

At the molecular level, CAS 28578-16-7 features a complex organic structure comprising a bromo group, a phenyl group, and a pentanone moiety. This molecular arrangement imparts specific chemical properties to the compound, making it valuable for organic synthesis. The chemical formula of CAS 28578-16-7 is C11H13BrO, with a molar mass of 241.12 g/mol.

Synthesis Methodology:

The synthesis of CAS 28578-16-7 typically involves multi-step organic reactions starting from commercially available starting materials. Various synthetic routes have been developed to access this compound, with a focus on efficiency, yield, and purity. Key steps may include bromination reactions, ketone functionalization, and purification techniques to obtain the desired product.

Physical and Chemical Properties:

Physically, CAS 28578-16-7 may exist as a colorless to pale yellow liquid or solid, depending on its purity and crystalline form. It is sparingly soluble in water but soluble in organic solvents such as ethanol and acetone. CAS 28578-16-7 exhibits specific characteristics such as melting point, boiling point, and stability, which are important for its handling and use in chemical processes. Chemically, the compound may undergo reactions such as bromination, oxidation, or reduction, leading to the formation of various derivatives.

Applications and Uses:

CAS 28578-16-7 serves as a crucial intermediate in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals. Its versatile chemistry makes it valuable as a building block for the synthesis of biologically active compounds, specialty chemicals, and advanced materials. Research efforts continue to explore novel applications and derivatives of CAS 28578-16-7 for various industrial and commercial purposes.

Environmental and Safety Considerations:

The production and use of CAS 28578-16-7 raise environmental and safety concerns related to chemical manufacturing processes and product handling. Proper storage, handling, and disposal practices are essential to minimize potential hazards and environmental impact. Regulatory compliance and risk management measures play a crucial role in ensuring the safe and responsible use of CAS 28578-16-7 in industrial settings.


In conclusion, CAS 28578-16-7 represents a valuable chemical compound with diverse applications and potential uses across multiple industries. Understanding its synthesis, properties, and applications is crucial for harnessing its full potential and ensuring its safe and sustainable use in various chemical processes. Ongoing research and innovation efforts are necessary to unlock new opportunities and address emerging challenges in the utilization of CAS 28578-16-7.

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